Morphological Description of Frontal EEG Interictal and Ictal Discharges in an Adult Cohort of 175 Patients

  1. Lloria-Gil, María Carmen
  2. García-López, Beatriz
  3. Wesenberg Kjaer, Troels
  4. Santamaría-Pelaéz, Mirian
  5. González-Santos, Josefa
  6. Sueiras-Gil, María
  7. Soto-Cámara, Raúl
  8. Gómez-Menéndez, Ana Isabel
  9. Vázquez-Sánchez, Fernando
  10. González-Bernal, Jerónimo J.
  1. 1 Complejo Asistencial Universitario de Burgos
    info

    Complejo Asistencial Universitario de Burgos

    Burgos, España

    ROR https://ror.org/01j5v0d02

  2. 2 Hospital Vall d'Hebron
    info

    Hospital Vall d'Hebron

    Barcelona, España

    ROR https://ror.org/03ba28x55

  3. 3 Universidad de Burgos
    info

    Universidad de Burgos

    Burgos, España

    ROR https://ror.org/049da5t36

  4. 4 Sankt Hans Hospital
    info

    Sankt Hans Hospital

    Roskilde, Dinamarca

    ROR https://ror.org/04d9g9604

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Revista:
Journal of Clinical Medicine

ISSN: 2077-0383

Año de publicación: 2021

Volumen: 10

Número: 6

Páginas: 1219

Tipo: Artículo

DOI: 10.3390/JCM10061219 GOOGLE SCHOLAR

Otras publicaciones en: Journal of Clinical Medicine

Resumen

Clinical and electroencephalogram (EEG) features in frontal lobe epilepsy (FLE) vary considerably among patients, making the diagnosis a challenge. The objective of this study was to describe interictal and ictal EEG activity, identifying variables that could help to differentiate and diagnose frontal lobe epilepsy cases. A prospective cross-sectional study from patients with frontal interictal epileptiform discharges (IED) referred to the Vall d’Hebron University Hospital (Barcelona, Spain) after a clinical event compatible with epileptic seizures was designed. The interictal and ictal activity were analyzed to provide a detailed EEG description of the cases, using different statistical analyses. The morphological seizure pattern at the ictal onset remained globally unchanged over time in seizures arising from the frontal lobe for each patient. Isolated sharp waves were the most frequent waveforms in the expression of IED. Frontal lobe seizures are frequently short and sometimes appear grouped in clusters within the same recording. Often the ictal expression of the electrical activity in frontal lobe seizure is subtle and challenging to interpret. A description of the main findings is summarized to identify seizures arising from the frontal lobe and avoid false negatives findings in EEG interpretations.

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