Identification of evolutionarily conserved gene networks mediating neurodegenerative dementia

  1. Swarup, V. 1
  2. Hinz, F.I. 1
  3. Rexach, J.E. 1
  4. Noguchi, K.-I. 2
  5. Toyoshiba, H. 2
  6. Oda, A. 2
  7. Hirai, K. 2
  8. Sarkar, A. 1
  9. Seyfried, N.T. 33
  10. Cheng, C. 4
  11. Haggarty, S.J. 4
  12. Ferrari, R. 8
  13. Rohrer, J.D. 8
  14. Ramasamy, A. 8
  15. Hardy, J. 8
  16. Hernandez, D.G. 9
  17. Nalls, M.A. 9
  18. Singleton, A.B. 9
  19. Kwok, J.B.J. 10
  20. Dobson-Stone, C. 10
  21. Brooks, W.S. 10
  22. Schofield, P.R. 10
  23. Halliday, G.M. 10
  24. Hodges, J.R. 10
  25. Piguet, O. 10
  26. Bartley, L. 10
  27. Thompson, E. 11
  28. Haan, E. 11
  29. Hernández, I. 12
  30. Ruiz, A. 12
  31. Boada, M. 12
  32. Borroni, B. 13
  33. Padovani, A. 13
  34. Cairns, N.J. 14
  35. Cruchaga, C. 14
  36. Binetti, G. 15
  37. Ghidoni, R. 15
  38. Benussi, L. 15
  39. Forloni, G. 16
  40. Albani, D. 16
  41. Galimberti, D. 1718
  42. Fenoglio, C. 1718
  43. Serpente, M. 1718
  44. Scarpini, E. 1718
  45. Clarimón, J. 19
  46. Lleó, A. 19
  47. Blesa, R. 19
  48. Waldö, M.L. 20
  49. Nilsson, K. 20
  50. Nilsson, C. 20
  51. Mackenzie, I.R.A. 21
  52. Hsiung, G.-Y.R. 21
  53. Mann, D.M.A. 22
  54. Grafman, J. 23
  55. Morris, C.M. 24
  56. Attems, J. 24
  57. Griffiths, T.D. 24
  58. McKeith, I.G. 24
  59. Thomas, A.J. 24
  60. Jaros, E. 24
  61. Pietrini, P. 25
  62. Huey, E.D. 26
  63. Wassermann, E.M. 27
  64. Tierney, M.C. 27
  65. Baborie, A. 28
  66. Pastor, P. 29
  67. Ortega-Cubero, S. 29
  68. Razquin, C. 30
  69. Alonso, E. 30
  70. Perneczky, R. 31
  71. Diehl-Schmid, J. 32
  72. Alexopoulos, P. 32
  73. Kurz, A. 32
  74. Rainero, I. 33
  75. Rubino, E. 33
  76. Pinessi, L. 33
  77. Rogaeva, E. 34
  78. George-Hyslop, P.S. 34
  79. Rossi, G. 35
  80. Tagliavini, F. 35
  81. Giaccone, G. 35
  82. Rowe, J.B. 36
  83. Schlachetzki, J.C.M. 37
  84. Uphill, J. 38
  85. Collinge, J. 38
  86. Mead, S. 38
  87. Danek, A. 39
  88. Van Deerlin, V.M. 66
  89. Grossman, M. 5
  90. Trojanowski, J.Q. 66
  91. Pickering-Brown, S. 40
  92. Momeni, P. 41
  93. van der Zee, J. 42
  94. Cruts, M. 42
  95. Van Broeckhoven, C. 42
  96. Cappa, S.F. 43
  97. Leber, I. 44
  98. Brice, A. 44
  99. Hannequin, D. 45
  100. Golfier, V. 46
  101. Vercelletto, M. 47
  102. Nacmias, B. 48
  103. Sorbi, S. 48
  104. Bagnoli, S. 48
  105. Piaceri, I. 48
  106. Nielsen, J.E. 49
  107. Hjermind, L.E. 49
  108. Riemenschneider, M. 50
  109. Mayhaus, M. 50
  110. Gasparoni, G. 50
  111. Pichler, S. 50
  112. Ibach, B. 51
  113. Rossor, M.N. 52
  114. Fox, N.C. 52
  115. Warren, J.D. 52
  116. Spillantini, M.G. 53
  117. Morris, H.R. 8
  118. Rizzu, P. 54
  119. Heutink, P. 54
  120. Snowden, J.S. 40
  121. Rollinson, S. 40
  122. Gerhard, A. 40
  123. Richardson, A. 55
  124. Bruni, A.C. 55
  125. Maletta, R. 55
  126. Frangipane, F. 55
  127. Cupidi, C. 55
  128. Bernardi, L. 55
  129. Anfossi, M. 55
  130. Gallo, M. 56
  131. Conidi, M.E. 56
  132. Smirne, N. 56
  133. Rademakers, R. 57
  134. Baker, M. 57
  135. Dickson, D.W. 57
  136. Graff-Radford, N.R. 57
  137. Petersen, R.C. 58
  138. Knopman, D. 58
  139. Josephs, K.A. 58
  140. Boeve, B.F. 58
  141. Parisi, J.E. 59
  142. Miller, B.L. 60
  143. Karydas, A.M. 60
  144. Rosen, H. 60
  145. Seeley, W.W. 60
  146. van Swieten, J.C. 61
  147. Dopper, E.G.P. 61
  148. Seelaar, H. 61
  149. Pijnenburg, Y.A.L. 62
  150. Scheltens, P. 62
  151. Logroscino, G. 63
  152. Capozzo, R. 63
  153. Novelli, V. 64
  154. Puca, A.A. 6566
  155. Franceschi, M. 67
  156. Postiglione, A. 68
  157. Milan, G. 69
  158. Sorrentino, P. 69
  159. Kristiansen, M. 70
  160. Chiang, H.-H. 71
  161. Graff, C. 71
  162. Pasquier, F. 72
  163. Rollin, A. 72
  164. Deramecourt, V. 72
  165. Lebouvier, T. 72
  166. Ferrucci, L. 73
  167. Kapogiannis, D. 74
  168. Grossman, M. 5
  169. Lah, J.J. 3
  170. Levey, A.I. 3
  171. Kondou, S. 2
  172. Geschwind, D.H. 117
  173. Show all authors +
  1. 1 David Geffen School of Medicine at UCLA
    info

    David Geffen School of Medicine at UCLA

    Los Ángeles, Estados Unidos

  2. 2 CNS Drug Discovery Unit, Pharmaceutical Research Division, Takeda Pharmaceutical Company Limited
  3. 3 Emory University School of Medicine
    info

    Emory University School of Medicine

    Atlanta, Estados Unidos

  4. 4 Massachusetts General Hospital
    info

    Massachusetts General Hospital

    Boston, Estados Unidos

    ROR https://ror.org/002pd6e78

  5. 5 Center for Neurodegenerative Disease Research, Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania
  6. 6 The Penn FTD Center, Department of Neurology, Perelman School of Medicine at the University of Pennsylvania
  7. 7 University of California Los Angeles
    info

    University of California Los Angeles

    Los Ángeles, Estados Unidos

    ROR https://ror.org/046rm7j60

  8. 8 University College London
    info

    University College London

    Londres, Reino Unido

    ROR https://ror.org/02jx3x895

  9. 9 Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health
  10. 10 Neuroscience Research Australia
    info

    Neuroscience Research Australia

    Sídney, Australia

    ROR https://ror.org/01g7s6g79

  11. 11 South Australian Clinical Genetics Service, Women’s and Children’s Hospital
  12. 12 Research Center and Memory Clinic of Fundació ACE, Institut Català de Neurociències Aplicades
  13. 13 Università degli Studi di Brescia
    info

    Università degli Studi di Brescia

    Brescia, Italia

    ROR https://ror.org/02q2d2610

  14. 14 Washington University in St. Louis School of Medicine
    info

    Washington University in St. Louis School of Medicine

    San Luis, Estados Unidos

  15. 15 IRCCS Istituto Centro San Giovanni di Dio – Fatebenefratelli
  16. 16 Biology of Neurodegenerative Disorders, IRCCS Istituto di Ricerche Farmacologiche
  17. 17 University of Milan
    info

    University of Milan

    Milán, Italia

    ROR https://ror.org/00wjc7c48

  18. 18 Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico
    info

    Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico

    Milán, Italia

    ROR https://ror.org/016zn0y21

  19. 19 Universitat Autònoma de Barcelona
    info

    Universitat Autònoma de Barcelona

    Barcelona, España

    ROR https://ror.org/052g8jq94

  20. 20 Lund University
    info

    Lund University

    Lund, Suecia

    ROR https://ror.org/012a77v79

  21. 21 University of British Columbia
    info

    University of British Columbia

    Vancouver, Canadá

    ROR https://ror.org/03rmrcq20

  22. 22 Institute of Brain, Behaviour and Mental Health, University of Manchester, Salford Royal Hospital
  23. 23 Departments of Physical Medicine and Rehabilitation, Psychiatry, and Cognitive Neurology and the Alzheimer’s Disease Center, Feinberg School of Medicine, Northwestern University
  24. 24 Newcastle University
    info

    Newcastle University

    Newcastle-upon-Tyne, Reino Unido

    ROR https://ror.org/01kj2bm70

  25. 25 IMT School for Advanced Studies, Lucca
  26. 26 Columbia University
    info

    Columbia University

    Nueva York, Estados Unidos

    ROR https://ror.org/00hj8s172

  27. 27 Behavioral Neurology Unit, National Insititute of Neurological Disorders and Stroke
  28. 28 University of Alberta
    info

    University of Alberta

    Edmonton, Canadá

    ROR https://ror.org/0160cpw27

  29. 29 Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas
    info

    Centro de Investigación Biomédica en Red sobre Enfermedades Neurodegenerativas

    Madrid, España

    ROR https://ror.org/00zca7903

  30. 30 Centro de Investigación Médica Aplicada
    info

    Centro de Investigación Médica Aplicada

    Pamplona, España

  31. 31 Imperial College London
    info

    Imperial College London

    Londres, Reino Unido

    ROR https://ror.org/041kmwe10

  32. 32 Technical University Munich
    info

    Technical University Munich

    Múnich, Alemania

    ROR https://ror.org/02kkvpp62

  33. 33 University of Turin
    info

    University of Turin

    Turín, Italia

    ROR https://ror.org/048tbm396

  34. 34 Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto
  35. 35 Division of Neurology V and Neuropathology, Fondazione IRCCS Istituto Neurologico Carlo Besta
  36. 36 Cambridge University Department of Clinical Neurosciences
  37. 37 Department of Cellular & Molecular Medicine, University of California San Diego
  38. 38 MRC Prion Unit, Department of Neurodegenerative Disease, UCL Institute of Neurology
  39. 39 Ludwig Maximilian University of Munich
    info

    Ludwig Maximilian University of Munich

    Múnich, Alemania

    ROR https://ror.org/05591te55

  40. 40 University of Manchester
    info

    University of Manchester

    Mánchester, Reino Unido

    ROR https://ror.org/027m9bs27

  41. 41 Laboratory of Neurogenetics, Department of Internal Medicine, Texas Tech University Health Science Center
  42. 42 Neurodegenerative Brain Diseases group, Department of Molecular Genetics, VIB
  43. 43 Neurorehabilitation Unit, Department of Clinical Neuroscience, Vita-Salute University and San Raffaele Scientific Institute
  44. 44 French Institute of Health and Medical Research
    info

    French Institute of Health and Medical Research

    París, Francia

    ROR https://ror.org/02vjkv261

  45. 45 Service de Neurologie, Rouen University Hospital
  46. 46 Service de Neurologie, CH
  47. 47 Service de Neurologie, CHU
  48. 48 University of Florence
    info

    University of Florence

    Florencia, Italia

    ROR https://ror.org/04jr1s763

  49. 49 Copenhagen University Hospital
    info

    Copenhagen University Hospital

    Copenhague, Dinamarca

    ROR https://ror.org/05bpbnx46

  50. 50 Saarland University Hospital, Laboratory for Neurogenetics
  51. 51 University of Regensburg
    info

    University of Regensburg

    Ratisbona, Alemania

    ROR https://ror.org/01eezs655

  52. 52 Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology
  53. 53 Department of Clinical Neurosciences, John Van Geest Brain Repair Centre, University of Cambridge
  54. 54 German Center for Neurodegenerative Diseases-Tübingen
  55. 55 Salford Royal Foundation Trust, Faculty of Medical and Human Sciences, University of Manchester
  56. 56 Regional Neurogenetic Centre, ASPCZ
  57. 57 Department of Neuroscience, Mayo Clinic Jacksonville
  58. 58 Department of Neurology, Mayo Clinic Rochester
  59. 59 Department of Pathology, Mayo Clinic Rochester
  60. 60 University of California, San Francisco
    info

    University of California, San Francisco

    San Francisco, Estados Unidos

    ROR https://ror.org/043mz5j54

  61. 61 Erasmus University Medical Center
    info

    Erasmus University Medical Center

    Róterdam, Holanda

    ROR https://ror.org/018906e22

  62. 62 VU University Medical Center
    info

    VU University Medical Center

    Ámsterdam, Holanda

    ROR https://ror.org/00q6h8f30

  63. 63 University of Bari Aldo Moro
    info

    University of Bari Aldo Moro

    Bari, Italia

    ROR https://ror.org/027ynra39

  64. 64 Medical Genetics Unit, Fondazione Policlinico Universitario Agostino Gemelli
  65. 65 Cardiovascular Research Unit, IRCCS Multimedica
  66. 66 Department of Medicine and Surgery, University of Salerno
  67. 67 Neurology Department, IRCCS Multimedica
  68. 68 University of Naples Federico II
    info

    University of Naples Federico II

    Nápoles, Italia

    ROR https://ror.org/05290cv24

  69. 69 Geriatric Center Frullone-ASL Napoli 1 Centro
  70. 70 UCL Genomics, Institute of Child Health (ICH), UCL
  71. 71 Karolinska Institute
    info

    Karolinska Institute

    Estocolmo, Suecia

    ROR https://ror.org/056d84691

  72. 72 University of Lille
  73. 73 Clinical Research Branch, National Institute on Aging
  74. 74 Cellular and Molecular Neuroscience Section, National Institute on Aging
Show affiliations +
Journal:
Nature Medicine

ISSN: 1546-170X

Year of publication: 2019

Volume: 25

Issue: 1

Pages: 152-164

Type: Article

DOI: 10.1038/S41591-018-0223-3 PMID: 30510257 SCOPUS: 2-s2.0-85058010718 GOOGLE SCHOLAR
Data source: Scopus