Susceptible genes and disease mechanisms identified in frontotemporal dementia and frontotemporal dementia with Amyotrophic Lateral Sclerosis by DNA-methylation and GWAS

  1. Taskesen, E. 12
  2. Mishra, A. 1
  3. van der Sluis, S. 1
  4. Ferrari, R. 3
  5. Veldink, J.H. 4
  6. van Es, M.A. 4
  7. Smit, A.B. 1
  8. Posthuma, D. 12
  9. Pijnenburg, Y. 2
  10. Hernandez, D.G. 5
  11. Nalls, M.A. 5
  12. Rohrer, J.D. 6
  13. Ramasamy, A. 7
  14. Kwok, J.B.J. 8
  15. Dobson-Stone, C. 8
  16. Schofield, P.R. 8
  17. Halliday, G.M. 8
  18. Hodges, J.R. 8
  19. Piguet, O. 8
  20. Bartley, L. 8
  21. Thompson, E. 9
  22. Haan, E. 9
  23. Hernández, I. 10
  24. Ruiz, A. 10
  25. Boada, M. 10
  26. Borroni, B. 11
  27. Padovani, A. 11
  28. Cruchaga, C. 12
  29. Cairns, N.J. 12
  30. Benussi, L. 13
  31. Binetti, G. 14
  32. Ghidoni, R. 13
  33. Forloni, G. 15
  34. Albani, D. 15
  35. Galimberti, D. 16
  36. Fenoglio, C. 16
  37. Serpente, M. 16
  38. Scarpini, E. 16
  39. Clarimón, J. 17
  40. Lleó, A. 17
  41. Blesa, R. 17
  42. Waldö, M.L. 18
  43. Nilsson, K. 18
  44. Nilsson, C. 18
  45. Mackenzie, I.R.A. 19
  46. Hsiung, G.-Y.R. 19
  47. Mann, D.M.A. 20
  48. Grafman, J. 21
  49. Morris, C.M. 22
  50. Attems, J. 22
  51. Griffiths, T.D. 22
  52. McKeith, I.G. 22
  53. Thomas, A.J. 22
  54. Pietrini, P. 23
  55. Huey, E.D. 24
  56. Wassermann, E.M. 25
  57. Baborie, A. 26
  58. Jaros, E. 22
  59. Tierney, M.C. 25
  60. Pastor, P. 27
  61. Razquin, C. 27
  62. Ortega-Cubero, S. 27
  63. Alonso, E. 27
  64. Perneczky, R. 28
  65. Diehl-Schmid, J. 29
  66. Alexopoulos, P. 29
  67. Kurz, A. 29
  68. Rainero, I. 30
  69. Rubino, E. 30
  70. Pinessi, L. 30
  71. Rogaeva, E. 31
  72. St George-Hyslop, P. 31
  73. Rossi, G. 32
  74. Tagliavini, F. 32
  75. Giaccone, G. 32
  76. Rowe, J.B. 33
  77. Schlachetzki, J.C.M. 34
  78. Uphill, J. 35
  79. Collinge, J. 35
  80. Mead, S. 35
  81. Danek, A. 36
  82. Van Deerlin, V.M. 37
  83. Grossman, M. 37
  84. Trojanowski, J.Q. 37
  85. van der Zee, J. 38
  86. Van Broeckhoven, C. 38
  87. Cappa, S.F. 39
  88. Leber, I. 40
  89. Hannequin, D. 41
  90. Golfier, V. 41
  91. Vercelletto, M. 41
  92. Brice, A. 40
  93. Nacmias, B. 42
  94. Sorbi, S. 42
  95. Bagnoli, S. 42
  96. Piaceri, I. 42
  97. Nielsen, J.E. 43
  98. Hjermind, L.E. 43
  99. Riemenschneider, M. 44
  100. Mayhaus, M. 44
  101. Ibach, B. 45
  102. Gasparoni, G. 44
  103. Pichler, S. 44
  104. Gu, W. 44
  105. Rossor, M.N. 6
  106. Fox, N.C. 6
  107. Warren, J.D. 6
  108. Spillantini, M.G. 46
  109. Morris, H.R. 3
  110. Rizzu, P. 47
  111. Heutink, P. 47
  112. Snowden, J.S. 20
  113. Rollinson, S. 20
  114. Richardson, A. 20
  115. Gerhard, A. 20
  116. Bruni, A.C. 48
  117. Maletta, R. 48
  118. Frangipane, F. 48
  119. Cupidi, C. 48
  120. Bernardi, L. 48
  121. Anfossi, M. 48
  122. Gallo, M. 48
  123. Conidi, M.E. 48
  124. Smirne, N. 48
  125. Rademakers, R. 49
  126. Baker, M. 49
  127. Dickson, D.W. 49
  128. Graff-Radford, N.R. 49
  129. Petersen, R.C. 50
  130. Knopman, D. 50
  131. Josephs, K.A. 50
  132. Boeve, B.F. 50
  133. Parisi, J.E. 50
  134. Seeley, W.W. 51
  135. Miller, B.L. 51
  136. Karydas, A.M. 51
  137. Rosen, H. 51
  138. van Swieten, J.C. 52
  139. Dopper, E.G.P. 52
  140. Seelaar, H. 52
  141. Scheltens, P. 53
  142. Logroscino, G. 54
  143. Capozzo, R. 54
  144. Novelli, V. 55
  145. Puca, A.A. 56
  146. Franceschi, M. 57
  147. Postiglione, A. 58
  148. Milan, G. 58
  149. Sorrentino, P. 58
  150. Kristiansen, M. 59
  151. Chiang, H.-H. 60
  152. Graff, C. 60
  153. Pasquier, F. 61
  154. Rollin, A. 61
  155. Deramecourt, V. 61
  156. Lebouvier, T. 61
  157. Kapogiannis, D. 62
  158. Ferrucci, L. 63
  159. Pickering-Brown, S. 20
  160. Singleton, A.B. 5
  161. Hardy, J. 3
  162. Momeni, P. 64
  163. Show all authors +
  1. 1 VU University Amsterdam
    info

    VU University Amsterdam

    Ámsterdam, Holanda

    ROR https://ror.org/008xxew50

  2. 2 VU University Medical Center (VUMC), Amsterdam Neuroscience
  3. 3 UCL London, Institute of Neurology, Department of Molecular Neuroscience
  4. 4 University Medical Center Utrecht
    info

    University Medical Center Utrecht

    Utrecht, Holanda

    ROR https://ror.org/0575yy874

  5. 5 Laboratory of Neurogenetics, National Institute on Aging, National Institutes of Health
  6. 6 Dementia Research Centre, Department of Neurodegenerative Disease, UCL Institute of Neurology
  7. 7 Department of Medical and Molecular Genetics, King’s College London Tower Wing, Guy’s Hospital
  8. 8 Neuroscience Research Australia
    info

    Neuroscience Research Australia

    Sídney, Australia

    ROR https://ror.org/01g7s6g79

  9. 9 South Australian Clinical Genetics Service, SA Pathology at Women’s and Children’s Hospital
  10. 10 Research Center and Memory Clinic of Fundació ACE, Institut Catal de Neurociències Aplicades
  11. 11 Università degli Studi di Brescia
    info

    Università degli Studi di Brescia

    Brescia, Italia

    ROR https://ror.org/02q2d2610

  12. 12 Washington University in St. Louis
    info

    Washington University in St. Louis

    San Luis, Estados Unidos

    ROR https://ror.org/01yc7t268

  13. 13 Molecular Markers Laboratory, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli
  14. 14 MAC Memory Clinic, IRCCS Istituto Centro San Giovanni di Dio Fatebenefratelli
  15. 15 Biology of Neurodegenerative Disorders, IRCCS Istituto di Ricerche Farmacologiche, “Mario Negri”
  16. 16 University of Milan
    info

    University of Milan

    Milán, Italia

    ROR https://ror.org/00wjc7c48

  17. 17 Universitat Autònoma de Barcelona
    info

    Universitat Autònoma de Barcelona

    Barcelona, España

    ROR https://ror.org/052g8jq94

  18. 18 Lund University
    info

    Lund University

    Lund, Suecia

    ROR https://ror.org/012a77v79

  19. 19 University of British Columbia
    info

    University of British Columbia

    Vancouver, Canadá

    ROR https://ror.org/03rmrcq20

  20. 20 Institute of Brain, Behaviour and Mental Health, University of Manchester, Salford Royal Hospital
  21. 21 Northwestern University
    info

    Northwestern University

    Evanston, Estados Unidos

    ROR https://ror.org/000e0be47

  22. 22 Newcastle University
    info

    Newcastle University

    Newcastle-upon-Tyne, Reino Unido

    ROR https://ror.org/01kj2bm70

  23. 23 IMT School for Advanced Studies
  24. 24 Columbia University
    info

    Columbia University

    Nueva York, Estados Unidos

    ROR https://ror.org/00hj8s172

  25. 25 National Institutes of Health
    info

    National Institutes of Health

    Bethesda, Estados Unidos

    ROR https://ror.org/01cwqze88

  26. 26 Department of Laboratory Medicine & Pathology, Walter Mackenzie Health Sciences Centre, 8440-112 St, University of Alberta Edmonton
  27. 27 Universidad de Navarra
    info

    Universidad de Navarra

    Pamplona, España

    ROR https://ror.org/02rxc7m23

  28. 28 Imperial College London
    info

    Imperial College London

    Londres, Reino Unido

    ROR https://ror.org/041kmwe10

  29. 29 Technical University Munich
    info

    Technical University Munich

    Múnich, Alemania

    ROR https://ror.org/02kkvpp62

  30. 30 University of Turin
    info

    University of Turin

    Turín, Italia

    ROR https://ror.org/048tbm396

  31. 31 Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto 60 Leonard Street, Toronto, Ontario, Canada
  32. 32 Division of Neurology V and Neuropathology, Fondazione IRCCS Istituto Neurologico Carlo Besta
  33. 33 University of Cambridge
    info

    University of Cambridge

    Cambridge, Reino Unido

    ROR https://ror.org/013meh722

  34. 34 University of California San Diego, Department of Cellular & Molecular Medicine
  35. 35 MRC Prion Unit, Department of Neurodegenerative Disease, UCL Institute of Neurology, Queen Square House
  36. 36 Ludwig Maximilian University of Munich
    info

    Ludwig Maximilian University of Munich

    Múnich, Alemania

    ROR https://ror.org/05591te55

  37. 37 University of Pennsylvania Perelman School of Medicine, Department of Pathology and Laboratory Medicine
  38. 38 Neurodegenerative Brain Diseases group, VIB-UAntwerp Center of Molecular Neurology, Antwerp, Belgium; Laboratory of Neurogenetics, Institute Born-Bunge, University of Antwerp
  39. 39 Neurorehabilitation Unit, Dept. Of Clinical Neuroscience, Vita-Salute University and San Raffaele Scientific Institute
  40. 40 French Institute of Health and Medical Research
    info

    French Institute of Health and Medical Research

    París, Francia

    ROR https://ror.org/02vjkv261

  41. 41 Service de Neurologie, Inserm U1079, CNR-MAJ, Rouen University Hospital
  42. 42 University of Florence
    info

    University of Florence

    Florencia, Italia

    ROR https://ror.org/04jr1s763

  43. 43 Copenhagen University Hospital
    info

    Copenhagen University Hospital

    Copenhague, Dinamarca

    ROR https://ror.org/05bpbnx46

  44. 44 Saarland University, Laboratory for Neurogenetics
  45. 45 University of Regensburg
    info

    University of Regensburg

    Ratisbona, Alemania

    ROR https://ror.org/01eezs655

  46. 46 University of Cambridge, Department of Clinical Neurosciences, John Van Geest Brain Repair Centre
  47. 47 German Center for Neurodegenerative Diseases-Tübingen
  48. 48 Regional Neurogenetic Centre, ASPCZ, Lamezia Terme
  49. 49 Department of Neuroscience, Mayo Clinic Jacksonville
  50. 50 Department of Neurology, Mayo Clinic Rochester
  51. 51 University of California, San Francisco
    info

    University of California, San Francisco

    San Francisco, Estados Unidos

    ROR https://ror.org/043mz5j54

  52. 52 Erasmus University Medical Center
    info

    Erasmus University Medical Center

    Róterdam, Holanda

    ROR https://ror.org/018906e22

  53. 53 VU University Medical Center
    info

    VU University Medical Center

    Ámsterdam, Holanda

    ROR https://ror.org/00q6h8f30

  54. 54 University of Bari Aldo Moro
    info

    University of Bari Aldo Moro

    Bari, Italia

    ROR https://ror.org/027ynra39

  55. 55 Medi cal Geneti cs Uni t, Fondazi one Policlinico Universitario A. Gemelli
  56. 56 Cardiovascular Research Unit, IRCCS Multimedica
  57. 57 Neurology Dept, IRCCS Multimedica
  58. 58 University of Naples Federico II
    info

    University of Naples Federico II

    Nápoles, Italia

    ROR https://ror.org/05290cv24

  59. 59 UCL Genomics, Institute of Child Health (ICH), UCL
  60. 60 Karolinska Institute
    info

    Karolinska Institute

    Estocolmo, Suecia

    ROR https://ror.org/056d84691

  61. 61 Univ Lille, DISTALZ
  62. 62 National Institute on Aging (NIA/NIH)
  63. 63 Clinical Research Branch, National Institute on Aging
  64. 64 Laboratory of Neurogenetics, Department of Internal Medicine, Texas Tech University Health Science Center
Journal:
Scientific Reports

ISSN: 2045-2322

Year of publication: 2017

Volume: 7

Issue: 1

Type: Article

DOI: 10.1038/S41598-017-09320-Z PMID: 28827549 SCOPUS: 2-s2.0-85029377334 GOOGLE SCHOLAR lock_openOpen access editor
Data source: Scopus