Asociación entre hipercolesterolemia y el uso de estatinas con el riesgo de glaucoma primario de ángulo abierto

  1. Patricia Pontón Méndez
  2. Renzo Renato Portilla Blanco
  3. Nuria Alonso-Santander
  4. I. Roberts Martínez-Aguirre
Zeitschrift:
MPG Journal

ISSN: 2171-9020

Datum der Publikation: 2019

Titel der Ausgabe: Dolor abdominal y colelitiasis, ¿es necesaria la colecistectomía?

Ausgabe: 2

Nummer: 45

Art: Artikel

Andere Publikationen in: MPG Journal

Zusammenfassung

The association between hypercholesterolemia and the use of statins with the appearance of and open angle primary glaucoma (OAPG) has been evaluated and there is an increased risk of OAPG with elevated serum cholesterol levels. It was also found that the use of statins decreased the risk of suffering from it, and that the longer the duration of use, the lower the risk of GPAA. However, its effect had never been evaluated after 5 years of treatment.

Bibliographische Referenzen

  • Hwang IC, Lee YJ, Bae JH. A meta-analysis of glaucoma risk in hyperlipidemic individuals: a critical problema in design. Invest Ophthalmol Vis Sci. 2016;57(14):6339-6340. doi:10.1167/iovs.16-20099
  • McCann P, Hogg RE, Fallis R, Azuara-Blanco A. The effect of statins on intraocular pressure  and on the incidence and progression of glaucoma: a systematic review and metaanalysis. Invest Ophthalmol Vis Sci. 2016;57:2729–2748. doi:10.1167/iovs.15-18595
  • Nagaoka T, Takahashi A, Sato E, et al. Effect of systemic administration of simvastatin on retinal circulation. Arch Ophthalmol. 2006;124(5):665-670. doi:10.1001/archopht.124.5.665
  • Song J, Deng PF, Stinnett SS, Epstein DL, Rao PV. Effects of cholesterol-lowering statins on the aqueous humor outflow pathway. Invest Ophthalmol Vis Sci. 2005;46(7):2424-2432. doi:10.1167/iovs.04-0776
  • Stein JD, Newman-Casey PA, Talwar N, Nan B, Richards JE, Musch DC. The relationship between statin use and open-angle glaucoma. Ophthalmology. 2012;119(10):2074-2081. doi:10.1016/j.ophtha.2012.04.029
  • Van der Most PJ, Dolga AM, Nijholt IM, Luiten PGM, Eisel ULM. Statins: mechanisms of neuroprotection. Prog Neurobiol. 2009;88(1):64-75. doi:10.1016/j.pneurobio.2009.02.002