CIENCIAS DE LA SALUD
Departamento
Instituto de Biología y Genética Molecular
Valladolid, EspañaPublikationen in Zusammenarbeit mit Forschern von Instituto de Biología y Genética Molecular (22)
2024
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In vitro and in vivo calibration of low affinity genetic Ca2+ indicators
Cell Calcium, Vol. 117
2023
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Pharmacological activation of insulin-degrading enzyme improves insulin secretion and glucose tolerance in diet-induced obese mice
Diabetes, Obesity and Metabolism, Vol. 25, Núm. 11, pp. 3268-3278
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Use of aequorin-based indicators for monitoring Ca2+ in acidic organelles
Biochimica et Biophysica Acta - Molecular Cell Research, Vol. 1870, Núm. 6
2022
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Insulin-degrading enzyme ablation in mouse pancreatic alpha cells triggers cell proliferation, hyperplasia and glucagon secretion dysregulation
Diabetologia, Vol. 65, Núm. 8, pp. 1375-1389
2021
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Targeting insulin-degrading enzyme in insulin clearance
International Journal of Molecular Sciences, Vol. 22, Núm. 5, pp. 1-21
2020
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Assessment of Insulin Tolerance Ex Vivo
Methods in molecular biology (Clifton, N.J.), Vol. 2128, pp. 291-300
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Assessment of Insulin Tolerance In Vivo in Mice
Methods in molecular biology (Clifton, N.J.), Vol. 2128, pp. 217-224
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Direct monitoring of ER Ca2+ dynamics reveals that Ca2+ entry induces ER-Ca2+ release in astrocytes
Pflugers Archiv European Journal of Physiology, Vol. 472, Núm. 4, pp. 439-448
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Hepatic insulin-degrading enzyme regulates glucose and insulin homeostasis in diet-induced obese mice
Metabolism: Clinical and Experimental, Vol. 113
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Sarcoplasmic reticulum Ca2+ decreases with age and correlates with the decline in muscle function in Drosophila
Journal of Cell Science, Vol. 133, Núm. 6
2019
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Pancreatic β-cell-specific deletion of insulin-degrading enzyme leads to dysregulated insulin secretion and β-cell functional immaturity
American journal of physiology. Endocrinology and metabolism, Vol. 317, Núm. 5, pp. E805-E819
2018
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Caffeine chelates calcium in the lumen of the endoplasmic reticulum
Biochemical Journal, Vol. 475, Núm. 22, pp. 3639-3649
2017
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Measuring Ca2 + inside intracellular organelles with luminescent and fluorescent aequorin-based sensors
Biochimica et Biophysica Acta - Molecular Cell Research, Vol. 1864, Núm. 6, pp. 894-899
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Using aequorin probes to measure Ca2+ in intracellular organelles
Cell Calcium, Vol. 64, pp. 3-11
2016
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GFP-Aequorin Protein Sensor for Ex Vivo and in Vivo Imaging of Ca2+ Dynamics in High-Ca2+ Organelles
Cell Chemical Biology, Vol. 23, Núm. 6, pp. 738-745
2015
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A new low-Ca2+ affinity GAP indicator to monitor high Ca2+ in organelles by luminescence
Cell Calcium, Vol. 58, Núm. 6, pp. 558-564
2014
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GAP, an aequorin-based fluorescent indicator for imaging Ca2+ in organelles
Proceedings of the National Academy of Sciences of the United States of America, Vol. 111, Núm. 7, pp. 2584-2589
2013
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Genotype-phenotype correlation in MMR mutation-positive families with Lynch syndrome
International Journal of Colorectal Disease, Vol. 28, Núm. 9, pp. 1195-1201
2012
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Comprehensive splicing functional analysis of DNA variants of the BRCA2 gene by hybrid minigenes
Breast Cancer Research, Vol. 14, Núm. 3
2010
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A high proportion of DNA variants of BRCA1 and BRCA2 is associated with aberrant splicing in breast/ovarian cancer patients
Clinical Cancer Research, Vol. 16, Núm. 6, pp. 1957-1967