Spatial correlations in the melting transition of DNA fibers submerged in solutions

  1. Adrián González Rodríguez 4
  2. Andrew Wildes 4
  3. Santiago Cuesta López 3
  4. Jean-Luc Garden 1
  5. Michel Peyrard 2
  1. 1 Institut Néel

    Institut Néel

    Grenoble, Francia


  2. 2 École Normale Supérieure de Lyon

    École Normale Supérieure de Lyon

    Lyon, Francia


  3. 3 Universidad de Burgos

    Universidad de Burgos

    Burgos, España


  4. 4 Institut Laue-Langevin

    Institut Laue-Langevin

    Grenoble, Francia


II Jornadas de Doctorandos de la Universidad de Burgos: Universidad de Burgos. 10 y 11 de diciembre de 2015
  1. Luis Antonio Sarabia Peinador (dir.)
  2. Miguel Ángel Iglesias Río (coord.)

Publisher: Servicio de Publicaciones e Imagen Institucional ; Universidad de Burgos

ISBN: 84-16283-16-8

Year of publication: 2015

Pages: 451-458

Congress: Jornadas de Doctorandos de la Universidad de Burgos (2. 2015. Burgos)

Type: Conference paper


The melting transition or thermal DNA is still not completely understood due to the lack of structural information during the transition. In recent years neutron scattering techniques have proved to be suitable to account for this lack of information. Specifically the melting of fiber DNA submerged in different solutions (‘’wet fibers’’) is mostly an unstudied avenue. In this work samples of fiber DNA in PEG and ethanol/water solutions are studied by DSC calorimetry, X-ray diffraction and neutron scattering in order to address the open questions about the optimal parameters for performing a melting experiment in wet DNA fibers.