Understanding DNA hairpins opening rates by mesoscopic model

  1. Marty Roda, Marta 1
  2. Cuesta López, Santiago 1
  3. Dahlen, Oda 2
  4. Erp, Titus S. van 2
  1. 1 Universidad de Burgos
    info

    Universidad de Burgos

    Burgos, España

    ROR https://ror.org/049da5t36

  2. 2 Norwegian University of Science and Technology
    info

    Norwegian University of Science and Technology

    Trondheim, Noruega

    ROR https://ror.org/05xg72x27

Book:
II Jornadas de Doctorandos de la Universidad de Burgos: Universidad de Burgos. 10 y 11 de diciembre de 2015
  1. Sarabia Peinador, Luis Antonio (dir.)
  2. Iglesias Río, Miguel Ángel (coord.)

Publisher: Servicio de Publicaciones e Imagen Institucional ; Universidad de Burgos

ISBN: 84-16283-16-8,  978-84-16283-18-7,  84-16283-18-4

Year of publication: 2015

Pages: 623-628

Congress: Jornadas de Doctorandos de la Universidad de Burgos (2. 2015. Burgos)

Type: Conference paper

DIALNET GOOGLE SCHOLAR

Abstract

We applied an adaptation of the PBD model to study hairpin denaturation for which experimental data are available. This is one of the firsts quantitative studies in which dynamical results from the mesoscopic PBD model have been compared with experiments. Our results shows that adding a entropic barrier to the potential of the PBD model, we can reproduce accurately the experiments results.

Data source: Dialnet