Understanding DNA hairpins opening rates by mesoscopic model
- Marty Roda, Marta 1
- Cuesta López, Santiago 1
- Dahlen, Oda 2
- Erp, Titus S. van 2
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1
Universidad de Burgos
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2
Norwegian University of Science and Technology
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- Sarabia Peinador, Luis Antonio (dir.)
- Iglesias Río, Miguel Ángel (coord.)
Editorial: Servicio de Publicaciones e Imagen Institucional ; Universidad de Burgos
ISBN: 84-16283-16-8, 978-84-16283-18-7, 84-16283-18-4
Ano de publicación: 2015
Páxinas: 623-628
Congreso: Jornadas de Doctorandos de la Universidad de Burgos (2. 2015. Burgos)
Tipo: Achega congreso
Resumo
We applied an adaptation of the PBD model to study hairpin denaturation for which experimental data are available. This is one of the firsts quantitative studies in which dynamical results from the mesoscopic PBD model have been compared with experiments. Our results shows that adding a entropic barrier to the potential of the PBD model, we can reproduce accurately the experiments results.
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