Spatial correlations in the melting transition of genomic fiber DNA in solution

  1. Adrián González Rodríguez 12
  2. Andrew Wildes 1
  3. Santiago Cuesta López 2
  4. Michel Peyrard 3
  1. 1 Institut Laue-Langevin

    Institut Laue-Langevin

    Grenoble, Francia


  2. 2 Universidad de Burgos

    Universidad de Burgos

    Burgos, España


  3. 3 École Normale Supérieure de Lyon

    École Normale Supérieure de Lyon

    Lyon, Francia


III Jornadas de Doctorandos de la Universidad de Burgos: Universidad de Burgos, 15 y 16 de diciembre de 2016
  1. Joaquín A. Pacheco Bonrostro (dir.)
  2. José Luis Cuesta Gómez (coord.)

Publisher: Servicio de Publicaciones e Imagen Institucional

ISBN: 978-84-16283-30-9

Year of publication: 2016

Pages: 285-290

Congress: Jornadas de Doctorandos de la Universidad de Burgos (3. 2016. Burgos)

Type: Conference paper


The melting of DNA is a phase transition which proves interesting due both to theoretical implications and current applications in bio-labs. Moreover it may have something to say in our general view of the statistic mechanic of DNA and s0 in our understanding of some biological processes. ln this work we use neutron scattering on highly oriented DNA fibers submerged in polymer solutions with different osmotic pressures aiming to study the effects of the DNA confinement on this still not totally understood transition. lt has been discovered that samples under higher osmotic pressure, this is more constricted, seems to undergo sharper meltings. Also, the nature of this submerged fibers seem to prevent the macroscopic collapse which hindered previous studies in similar humidified samples.